RecruitingNot ApplicableNCT05894746

Gfree - For Improved Blood Sugar and Reduced Inflammation.

GFREE - A Study for Improved Blood Sugar Levels, Reduced Inflammation and for Increasing Knowledge of the Connection Between Diabetes and COVID-19.


Sponsor

Göteborg University

Enrollment

60 participants

Start Date

May 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to reduce inflammation and improve glycemic control in healthy volunteers, parents, as well as children, adolescents and adults with or without diabetes. The main questions it aims to answer are: • does a reduction wheat gluten improve glycemic control and/or inflammatory biomarkers • does a reduction in certain amino acids (which is most common in wheat gluten) improve glycemic control and/or inflammatory biomarkers • can we identify individuals with an inflammatory response, which leads to poor glycemic control. Participants will eat gluten-free products as well as similar products containing gluten. They will also eat gluten together with probiotics to see if an effect of gluten can be reduced. Researchers will compare everyone with themselves (cross-over design) and if possible individuals with and without diabetes.


Eligibility

Min Age: 6 Years

Inclusion Criteria1

  • \- none

Exclusion Criteria1

  • \- A diagnosis of celiac disease

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Interventions

DIETARY_SUPPLEMENTgluten-free

see info in arm description

DIETARY_SUPPLEMENTprobiotic

see info in arm description

DIETARY_SUPPLEMENTgluten

see info in arm description


Locations(2)

Sahlgrenska University Hospital

Gothenburg, Sweden

University of Skövde

Skövde, Sweden

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NCT05894746


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