RecruitingPhase 4NCT05898087

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty


Sponsor

Connecticut Children's Medical Center

Enrollment

128 participants

Start Date

Apr 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 30cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 30cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.


Eligibility

Min Age: 13 YearsMax Age: 25 Years

Inclusion Criteria5

  • Female
  • Age 13-25 at the time of surgery
  • Undergoing bilateral reduction mammaplasty at Connecticut Children's from 1/1/2022-12/31/2025.
  • Ability of child's parent/legal guardian to understand and the willingness to sign a written informed consent document.
  • Patients lost to follow-up- they must be seen within 1 week and 4 weeks post-operatively

Exclusion Criteria7

  • Patients with history of substance use disorder or "chronic pain" defined as pain requiring management and treatment by a pain management specialist.
  • Patients already taking narcotics at the time of surgery.
  • Patients with a history of hepatic or renal dysfunction.
  • Patients with known allergy to bupivacaine.
  • Patients who are pregnant, determined by urine testing in pre-operative area.
  • Patients who are non-verbal or have developmental delays that would result in inability to report reliable pain scores.
  • Patients with significant post-operative complications

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Interventions

DRUGMarcaine 0.25 % Injectable Solution

Patients in this arm will receive an injection of 20cc of injectable 0.25% bupivacaine solution. It will be injected in a fan-like pattern beneath the pectoralis fascia

DRUGSaline

Patients in this arm will receive an injection of 20cc of injectable saline. It will be injected in a fan-like pattern beneath the pectoralis fascia


Locations(2)

Connecticut Children's

Farmington, Connecticut, United States

Connecticut Children's

Hartford, Connecticut, United States

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NCT05898087


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