RecruitingNCT05903430

A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy (MIDSECTION)

A Feasibility Study of MRI Guided Stereotactic Ablative Radiotherapy


Sponsor

The Christie NHS Foundation Trust

Enrollment

60 participants

Start Date

Aug 29, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

To determine if the investigators are able to deliver highly focused, intense radiation to tumours in the abdominal region or chest cavity whilst limiting the dose to surrounding organs using a high field strength MR-Linac.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether MRI-guided stereotactic ablative radiotherapy (SABR) — a highly precise form of radiation that is guided in real-time by MRI imaging — is feasible and acceptable for treating tumors in the abdomen or centrally located lung tumors. **You may be eligible if...** - You have no MRI contraindications (e.g., no metal implants that are MRI-incompatible) - You are eligible for abdominal or central lung SABR (a precise, few-session radiation treatment) according to established guidelines - You have no more than 3 sites of oligometastatic disease (a small number of cancer spread sites) - Your general health is adequate (performance status ≤2) - Your life expectancy is greater than 6 months - You are willing to attend follow-up visits for at least 1 year **You may NOT be eligible if...** - You have a contraindication to MRI - You cannot tolerate lying in an MRI machine - You have serious uncontrolled medical conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

The Christie NHS Foundation Trust

Manchester, United Kingdom, United Kingdom

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NCT05903430


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