RecruitingPhase 3NCT05903859

Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)


Sponsor

University of Miami

Enrollment

90 participants

Start Date

Jan 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm motility in men with spinal cord injuries. The medicine is called probenecid.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo, a drug called Probenecid 500 Milligrams (mg), and others for people with infertility, male. The study is currently recruiting participants at 1 location. People eligible for this study include men aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGProbenecid 500 Milligrams (mg)

Participants in this group will receive 500 mg of probenecid by mouth twice a day for a total of 90 days.

DRUGprobenecid 250 Milligrams (mg)

Participants in this group will receive 250 mg of probenecid by mouth twice a day for a total of 90 days.

DRUGPlacebo

Participants in this group will receive a placebo pill by mouth twice a day for a total of 90 days.


Locations(1)

University of Miami

Miami, Florida, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05903859


Related Trials