RecruitingPhase 1NCT05906433

Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis

Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis.


Sponsor

Foundation for Orthopaedic Research and Education

Enrollment

75 participants

Start Date

Jun 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients must be 18 years of age and be able to consent for themselves.
  • OA grade Kellgren Lawrence Stage II or III.
  • Diagnosis of primary osteoarthritis.

Exclusion Criteria4

  • Patients with other forms of arthritis such as inflammatory arthritis.
  • History of narcotic use for the past 6 months.
  • Kellgren Lawrence arthritis grade 1 or 4.
  • Pregnant women and prisoners.

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Interventions

DRUGKenalog with bupivacaine Injection

Indications, relevant for this study include Kenalog injection for knee pain from osteoarthritis or inflammatory arthritis. A single injection to a patient who has no known allergies to anesthetic or corticosteroids would be administered during a scheduled clinical visit.


Locations(1)

Florida Orthopaedic Institute

Tampa, Florida, United States

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NCT05906433


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