RecruitingNot ApplicableNCT05929911

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD


Sponsor

Montefiore Medical Center

Enrollment

20 participants

Start Date

Apr 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study tests a type of psychotherapy called Trauma-Focused Psychodynamic Psychotherapy (TFPP) — which helps people process traumatic memories — in people living with HIV who also have PTSD (post-traumatic stress disorder). **You may be eligible if...** - You have been diagnosed with PTSD (confirmed by a clinical interview) - You are living with HIV (confirmed by medical records or testing) - Your psychiatric medications have been stable for at least 2 months **You may NOT be eligible if...** - You have active psychosis or bipolar I disorder - You are at acute risk of suicide - You currently have a substance use disorder - You have a significant cognitive impairment or organic brain disorder - You have unstable medical conditions unrelated to HIV Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTrauma-focused psychodynamic psychotherapy

This psychotherapy addresses disruptions in the ability to reflect and affective regulation by exploring the psychological meanings of symptoms and their relation to traumatic events. The therapist works to identify intrapsychic conflicts, intense negative affects, and defense mechanisms related to the PTSD syndrome using a psychodynamic formulation that provides a framework for intervention. The transference provides a forum for patients to address feelings of mistrust, difficulties with authority, fears of abuse, angry and guilty feelings, and fantasies. This treatment will be provided in-person or over teletherapy as the public health situation demands.


Locations(1)

Albert Einstein College of Medicine

The Bronx, New York, United States

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NCT05929911


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