Post Traumatic Stress Disorder (PTSD) Clinical Trials

33 recruitingLast updated: June 18, 2026

There are 33 actively recruiting post traumatic stress disorder (ptsd) clinical trials across 14 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3. Top locations include San Antonio, Texas, United States, San Diego, California, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Post Traumatic Stress Disorder (PTSD) Trials at a Glance

33 actively recruiting trials for post traumatic stress disorder (ptsd) are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 24 trials, with the heaviest enrollment activity in San Antonio, San Diego, and Houston. Lead sponsors running post traumatic stress disorder (ptsd) studies include VA Office of Research and Development, Pharmacotherapies for Alcohol and Substance Use Disorders Alliance, and Istanbul University.

Browse post traumatic stress disorder (ptsd) trials by phase

Treatments under study

About Post Traumatic Stress Disorder (PTSD) Clinical Trials

Looking for clinical trials for Post Traumatic Stress Disorder (PTSD)? There are currently 39 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Post Traumatic Stress Disorder (PTSD) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Post Traumatic Stress Disorder (PTSD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Not Applicable

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Post Traumatic Stress Disorder (PTSD)HIV
Montefiore Medical Center20 enrolled1 locationNCT05929911
Recruiting

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Yale University160 enrolled1 locationNCT07488819
Recruiting
Not Applicable

The Efficacy and Safety of Temporal Interference Stimulation in the Treatment of Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Shanghai Mental Health Center5 enrolled1 locationNCT07644338
Recruiting
Not Applicable

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

Post Traumatic Stress Disorder (PTSD)Opioid-use DisorderIntimate Partner Violence (IPV)
Yale University532 enrolled3 locationsNCT07115030
Recruiting
Not Applicable

Psychosocial Factors and Efficacy of Remote Cognitive Remediation for Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Université du Québec a Montréal64 enrolled1 locationNCT07309302
Recruiting
Not Applicable

TMS for PTSD in Youth

Post Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center at San Antonio20 enrolled1 locationNCT07401225
Recruiting
Phase 2

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)
VA Office of Research and Development240 enrolled1 locationNCT06194851
Recruiting
Not Applicable

Nurse-Led PTSD Treatment in Primary Care

Post Traumatic Stress Disorder (PTSD)
Rush University Medical Center100 enrolled2 locationsNCT07430657
Recruiting
Not Applicable

Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

Post Traumatic Stress DisorderPost Traumatic Stress Disorder (PTSD)PTSD+2 more
Acacia Clinics40 enrolled1 locationNCT07523685
Recruiting
Not Applicable

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Depressive DisorderPost Traumatic Stress Disorder (PTSD)Eating Disorders+3 more
Peking University464 enrolled1 locationNCT07458100
Recruiting
Not Applicable

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

Chronic PainPost Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center, Houston146 enrolled2 locationsNCT07116109
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Not Applicable

EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study

NeoplasmPsychological DistressPost Traumatic Stress Disorder (PTSD)+1 more
Università Cattolica di Milano25 enrolled1 locationNCT07447089
Recruiting
Not Applicable

Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion

Post Traumatic Stress Disorder (PTSD)
Umeå University40 enrolled1 locationNCT07407946
Recruiting
Not Applicable

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Brigham and Women's Hospital40 enrolled1 locationNCT07245641
Recruiting
Not Applicable

Building Ukraine's Strength in PTSD Treatment and Research

Post Traumatic Stress DisorderPost Traumatic Stress Disorder (PTSD)
University of Luxembourg120 enrolled2 locationsNCT07318181
Recruiting
Not Applicable

Mind-body Skills Groups for War-Related Trauma in Adolescents in Gaza

Post Traumatic Stress Disorder (PTSD)
The Center for Mind-Body Medicine120 enrolled1 locationNCT07302984
Recruiting
Not Applicable

Evaluating Treatments for Suicidal Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)Self-directed Violence
VA Office of Research and Development125 enrolled4 locationsNCT05974631
Recruiting
Phase 2Phase 3

Software as a Medical Device for the Treatment of Patients With PTSD

Post Traumatic Stress Disorder (PTSD)
Otsuka Medical Devices Co., Ltd. Japan52 enrolled35 locationsNCT06589505
Recruiting
Not Applicable

Developing Innovative PTSD Treatment for Children

Post Traumatic Stress Disorder (PTSD)
Viktoriia Gorbunova40 enrolled1 locationNCT07185126