Post Traumatic Stress Disorder (PTSD) Clinical Trials

24 recruiting

Frequently Asked Questions

Common questions about Post Traumatic Stress Disorder (PTSD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 24 trials

Recruiting
Not Applicable

EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study

NeoplasmPsychological DistressPost Traumatic Stress Disorder (PTSD)+1 more
Università Cattolica di Milano25 enrolled1 locationNCT07447089
Recruiting
Not Applicable

Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion

Post Traumatic Stress Disorder (PTSD)
Umeå University40 enrolled1 locationNCT07407946
Recruiting
Not Applicable

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Brigham and Women's Hospital40 enrolled1 locationNCT07245641
Recruiting
Not Applicable

Building Ukraine's Strength in PTSD Treatment and Research

Post Traumatic Stress DisorderPost Traumatic Stress Disorder (PTSD)
University of Luxembourg120 enrolled2 locationsNCT07318181
Recruiting
Not Applicable

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

Chronic PainPost Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center, Houston146 enrolled1 locationNCT07116109
Recruiting
Not Applicable

Psychosocial Factors and Efficacy of Remote Cognitive Remediation for Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Université du Québec a Montréal64 enrolled1 locationNCT07309302
Recruiting
Not Applicable

Mind-body Skills Groups for War-Related Trauma in Adolescents in Gaza

Post Traumatic Stress Disorder (PTSD)
The Center for Mind-Body Medicine120 enrolled1 locationNCT07302984
Recruiting
Not Applicable

Evaluating Treatments for Suicidal Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)Self-directed Violence
VA Office of Research and Development125 enrolled4 locationsNCT05974631
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 2Phase 3

Software as a Medical Device for the Treatment of Patients With PTSD

Post Traumatic Stress Disorder (PTSD)
Otsuka Medical Devices Co., Ltd. Japan52 enrolled35 locationsNCT06589505
Recruiting
Not Applicable

Developing Innovative PTSD Treatment for Children

Post Traumatic Stress Disorder (PTSD)
Viktoriia Gorbunova40 enrolled1 locationNCT07185126
Recruiting
Phase 1

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Not Applicable

NightWare and Cardiovascular Health in Veterans With PTSD

Autonomic DysfunctionCardiovascular DiseasesEndothelial Dysfunction+4 more
VA Office of Research and Development125 enrolled1 locationNCT06419959
Recruiting
Not Applicable

Brief Videos Delivered by Text Messages as a Public Health Intervention for PTSD in Youth

Post Traumatic Stress Disorder (PTSD)Post-Traumatic Stress Disorder in AdolescencePost-Traumatic Stress Disorder in Youth
IWK Health Centre98 enrolled1 locationNCT07165782
Recruiting
Not Applicable

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

DepressionAnxietyPost Traumatic Stress Disorder (PTSD)
VA Office of Research and Development300 enrolled4 locationsNCT06162741
Recruiting
Phase 2

Suvorexant for Treatment of AUD and PTSD

InsomniaPost Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance76 enrolled2 locationsNCT06679062
Recruiting
Not Applicable

Shared Decision Making in PTSD Treatment

Post Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center at San Antonio200 enrolled2 locationsNCT06953687
Recruiting
Phase 2

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)
VA Office of Research and Development240 enrolled1 locationNCT06194851
Recruiting
Not Applicable

Hexadecanal as an Addon to Cognitive Processing Therapy for PTSD

Post Traumatic Stress Disorder (PTSD)
Tel Aviv University40 enrolled1 locationNCT06968312
Recruiting

Follow-Up Study on Children Exposed to Trauma

Post Traumatic Stress Disorder (PTSD)Complex Post-Traumatic Stress Disorder (CPTSD)
Istanbul University210 enrolled1 locationNCT06975852