Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

This study, called Project Khanya, is testing a peer-delivered program in South Africa to help people living with HIV who also struggle with substance use (like alcohol or drugs) take their HIV medications more consistently. Trained peers (people with similar lived experiences) deliver the support program. **You may be eligible if...** - You are HIV-positive and on antiretroviral therapy (ART — HIV medications) - You are 18 or older - You have had at least moderate substance use (alcohol or drugs other than tobacco) in the past 3 months - You have struggled to take your HIV medications consistently — such as missing appointments, having a detectable viral load, or being on second/third-line HIV treatment **You may NOT be eligible if...** - You have severe opiate dependence (since opiate replacement therapy is not widely available) - You have severe alcohol dependence that requires medical management - You are currently in another HIV medication study Talk to your doctor to see if this trial is right for you.