Drug Use Clinical Trials

11 recruiting

Frequently Asked Questions

Common questions about Drug Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 4

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

HIVSubstance Use Disorder (SUD)Injection Drug Use
Massachusetts General Hospital100 enrolled2 locationsNCT07199335
Recruiting
Phase 4

Implementing Low-Barrier HCV Treatment in a Jail Setting

Implementation ScienceIncarcerationInjection Drug Use+1 more
Lifespan40 enrolled1 locationNCT06953479
Recruiting
Phase 2

Family Acceptance Project Online (Pilot RCT)

DepressionAnxietyDrug Use+6 more
University of Michigan180 enrolled1 locationNCT06839859
Recruiting
Not Applicable

Reducing Stigma in People Who Inject Drugs (PWID) With HIV Using a Rapid Start Antiretroviral Therapy Intervention (ART)

HIVDrug Use
Yale University135 enrolled3 locationsNCT06541028
Recruiting
Not Applicable

Lakota Family Acceptance Project

DepressionAnxietyDrug Use+6 more
University of Michigan28 enrolled2 locationsNCT07326748
Recruiting
Not Applicable

Families With Pride ("Familias Con Orgullo").

DepressionDrug Use
University of Miami306 enrolled1 locationNCT06057337
Recruiting
Not Applicable

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

Opioid UseHIV InfectionsSubstance Use Disorders+3 more
Johns Hopkins University360 enrolled2 locationsNCT06103370
Recruiting

Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries

HepatitisHIVDrug Use
Médecins du Monde2,400 enrolled9 locationsNCT06395129
Recruiting
Not Applicable

Project Vuselela Feasibility

HIVDrug Users
Arizona State University80 enrolled1 locationNCT07117656
Recruiting
Not Applicable

Mental Health in Primary Care

Depression, AnxietySuicideDrug Use
University of Miami468 enrolled17 locationsNCT05426057
Recruiting
Phase 4

Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use

Immune DysregulationHIVSystemic Inflammation+1 more
University of Alabama at Birmingham100 enrolled1 locationNCT06829238
Recruiting
Phase 4

Morning Versus Bedtime Dosing of Antihypertensive Medication

HypertensionBlood PressureDrug Use
Yan Li300 enrolled1 locationNCT05089448
Recruiting
Phase 2

NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC

Advanced CancerPancreatic AdenocarcinomaCapecitabine+5 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences30 enrolled1 locationNCT06405490
Recruiting
Not Applicable

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Substance UseDrug UseHuman Immunodeficiency Virus+1 more
University of Maryland, College Park160 enrolled1 locationNCT05933226
Recruiting

Active Pharmacovigilance Study of the Medicine Rinvoq™ (Upadacitinib)

Adverse Drug EventDrug UseDrug Side Effect+3 more
Universidade do Porto150 enrolled3 locationsNCT06498167