Adipose Tissue Storage in the Rapid Remission of Hepatic and Cardiac Metabolic Dysfunction After Bariatric Surgery

This study is examining how bariatric (weight loss) surgery rapidly improves liver and heart health by changing how fat is stored in the body. Researchers will compare outcomes in patients with and without type 2 diabetes who undergo bariatric surgery. **You may be eligible if...** - You are aged 18–65 - You have a BMI of 35 kg/m² or above (severely obese) - You have been diagnosed with type 2 diabetes OR you do not have type 2 diabetes - Women must have a negative pregnancy test **You may NOT be eligible if...** - You currently take certain medications (oral contraceptives, fibrates, thiazolidinediones, insulin, or beta-blockers) that affect metabolism and cannot be temporarily stopped - You have overt cardiovascular disease, liver failure, kidney failure, or other uncontrolled medical conditions - You smoke or drink more than 2 alcoholic beverages per day - You have a contraindication to surgery or cannot temporarily stop your diabetes/lipid/blood pressure medications Talk to your doctor to see if this trial is right for you.