RecruitingNot ApplicableNCT05944146

Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients


Sponsor

Shanghai Zhongshan Hospital

Enrollment

200 participants

Start Date

May 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • adult cardiac surgery patients
  • with thermodilution technique monitoring
  • mechanical ventilation

Exclusion Criteria4

  • life threatening arrhythmia
  • severe valve regurgitation
  • left ventricular ejection fraction less than 30%
  • patients with mechanical circulatory support

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Interventions

BEHAVIORALpassive leg raising

transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

DRUGDobutamine

infusion dobutamine


Locations(1)

Zhongshan hospital Fudan University

Shanghai, Shanghai Municipality, China

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NCT05944146


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