RecruitingNCT05945576

IDMet (RaDiCo Cohort) (RaDiCo-IDMet)

National Cohort on Imprinting Disorders and Their Metabolic Consequences


Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

2,000 participants

Start Date

Mar 10, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to describe the natural history of imprinting disorders (IDs) according to their metabolic profile in all patients (adults and children) affected with an ID regardless of the severity of the disease, with a molecular characterization, with a signed informed consent for all subjects, followed in one partner's center. The main questions it aims to answer are: * Can we identify common metabolic profiles for all imprinted diseases? * Which imprinting disorders have an impact on the metabolic profiles of IDs? * Which are the metabolic risks associated to IDs? * Can we use the metabolic profiles for the clinical classification and prognosis of IDs? * Are there common therapeutic approaches for all IDs?


Eligibility

Inclusion Criteria3

  • Patients (adults and children) affected with an ID regardless of the severity of the disease
  • A confirmed diagnosis of ID (based on molecular diagnosis)
  • A signed informed consent for adults or signed informed consent of parents/guardians of minors/ protected adult.

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Locations(20)

CHU d'Angers

Angers, France

Hôpital Jean Minjoz

Besançon, France

Hôpital Gabriel Montpied

Clermont-Ferrand, France

Hôpital Bicêtre

Le Kremlin-Bicêtre, France

Hôpital Jeanne de Flandre

Lille, France

Hôpital de la mère et de l'enfant

Limoges, France

Hôpital Femme Mère Enfant

Lyon, France

Hôpital de la Timone

Marseille, France

Hôpital Brabois

Nancy, France

Hôpital enfant-adolescent

Nantes, France

Hôpital Armand-Trousseau

Paris, France

Hôpital de la Pitié-Salpêtrière

Paris, France

Hôpital de la Pitié-Salpêtrière

Paris, France

Hôpital Necker Enfants Malades

Paris, France

Hôpital Robert Debré

Paris, France

Hôpital Sud

Rennes, France

Hôpital Civil

Strasbourg, France

Hôpital des Enfants

Toulouse, France

Hôpital des Enfants

Toulouse, France

Hôpital Bretonneau

Tours, France

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NCT05945576


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