RecruitingNot ApplicableNCT05945641

Effect of Low-load Resistance Training vs. High-intensity Interval Training on Local Muscle Endurance

The Effect of Low-Load Resistance Training Versus High-intensity/Sprint Interval Training on Local Muscle Endurance, Mitochondrial Content, Mitochondrial Function, and Muscle Capillarization


Sponsor

University of British Columbia

Enrollment

20 participants

Start Date

Sep 27, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Local muscle endurance (LME) is the ability of a muscle(s) to resist fatigue and is needed for daily activities of life such as climbing stairs, lifting/moving objects, and in sport contexts like rock climbing, mixed martial arts, cross-fit, kayaking and canoeing. Therefore, the investigators want learn how to improve LME and understand what in human bodies changes during exercise training to cause these changes. The investigators know that lifting weights improves muscle strength which is believed to improve LME. Specifically lifting less heavy weights (LLRET) for more repetitions leads to greater gains in LME opposed to heavier weights for fewer repetitions. Therefore, lifting less heavy weights likely causes greater changes in our muscles than lifting heavier weights that cause improvements in LME. Aerobic exercise preformed at high intensities in an interval format (HIIT) may also help improve LME by increasing our muscle's ability to produce energy during exercise. Therefore, the investigators want to see which of LLRET or HIIT leads to greater improvements in LME.


Eligibility

Min Age: 19 YearsMax Age: 30 Years

Inclusion Criteria4

  • Able to understand and communicate in English
  • 19-30 years of age
  • All "No" answers on the CSEP Get Active questionnaire or doctors' approval to participate
  • Untrained participants: no structured resistance and/or endurance training over the past 12-months (i.e., >2 hours per week of structured/periodized training)

Exclusion Criteria8

  • BMI lower than 18 or greater than 30
  • Current use of cigarettes or other nicotine devices
  • Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
  • Any medical condition impacting the ability to participate in maximal exercise
  • Type one or type two diabetes
  • Diagnosis of cancer or undergoing cancer treatment in the past 12 months
  • Taking blood-thinning medication or the presence of a bleeding disorder
  • Drug therapy with any drugs that alter skeletal muscle metabolism (i.e., Metformin, Benzodiazepines)

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Interventions

BEHAVIORALLow Load Resistance training

Performing single leg knee extension exercise with using equivalent to \~30%1-RM to failure,

BEHAVIORALSprint/High Intensity Interval Training

Performing repeated submaximal/maximal 30second-60 seconds (1-3 minute rest between) aerobic intervals on a Kicking ergometer (modified bike that allows cycling to be performed with one leg using a kicking motion).


Locations(1)

Univeristy if British Columbia

Vancouver, British Columbia, Canada

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NCT05945641


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