Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
Adaptive Working Memory and Physical Exercise Training to Improve Brain and Mitochondrial Function in MCI
University of Maryland, Baltimore
90 participants
Jan 8, 2024
INTERVENTIONAL
Conditions
Summary
The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed. The current exploratory project aims to evaluate and understand how the brain and cognition may improve after a 12-week intervention that combines brain training and aerobic exercise training to improve brain function, both in those with mild cognitive impairment (some with possible prodromal Alzheimer's disease) and with healthy aging. Findings from this pilot project will guide and refine the development of a future larger clinical trial that aligns with the goals of the National Alzheimer's Plan of Action (NAPA), especially regarding "Prevent and Effectively Treat Alzheimer's Disease (AD) by 2025.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Progressive aerobic exercise
Adaptive cognitive training
Combine adaptive cognitive and progressive aerobic exercise training
Locations(1)
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NCT05948930