RecruitingNot ApplicableNCT05950919

Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia

Z 32201 - Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia: A Type II Hybrid Effectiveness-implementation Stepped Wedge Trial


Sponsor

University of North Carolina, Chapel Hill

Enrollment

5,620 participants

Start Date

May 30, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the effects of a multi-level intervention known as "TASKPEN," adapted from the World Health Organization (WHO) Package of Essential Noncommunicable Disease Interventions (WHO-PEN) for the Zambian public health system, on clinical and implementation outcomes for persons living with HIV (PLHIV) with co-morbid cardio-metabolic conditions in Lusaka, Zambia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial tests a package of evidence-based care strategies to help people living with HIV in Zambia who also have heart disease, diabetes, high blood pressure, or other metabolic conditions. **You may be eligible if...** - You are an adult (18+) living with HIV and receiving HIV care at a study site in Lusaka, Zambia - For the nested cohort: you also have high blood pressure, diabetes, prediabetes, high cholesterol, or you currently smoke tobacco **You may NOT be eligible if...** - You have no documented HIV diagnosis - You are visiting only once or plan to transfer your care elsewhere - You previously participated in a study survey at the same site - You are unable or unwilling to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTASKPEN

The package of integrated HIV/NCD services: 1. Integrated non-communicable/HIV care ("one stop shop" for services) 2. WHO PEN protocols, algorithm, \& training materials adapted for Zambia 3. Access to cardio-metabolic condition screening \& laboratory monitoring 4. Non-communicable disease-focused electronic medical record module 5. Strengthened NCD medication supply chain


Locations(12)

Bauleni Health Center

Lusaka, Zambia

Chawama 1st Level Hospital

Lusaka, Zambia

Chelstone Urban Health Center

Lusaka, Zambia

Chipata 1st Level Hospital

Lusaka, Zambia

Kabwata Urban Health Center

Lusaka, Zambia

Kalingalinga Urban Health Center

Lusaka, Zambia

Kamwala Urban Health Center

Lusaka, Zambia

Kanyama 1st Level Hospital

Lusaka, Zambia

Makeni Urban Health Center

Lusaka, Zambia

Mtendere Health Center

Lusaka, Zambia

Ng'ombe Urban Health Center

Lusaka, Zambia

Railway Urban Health Center

Lusaka, Zambia

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NCT05950919


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