90Y Transarterial Radioembolization Versus Microwave Ablation in Small Hepatocellular Carcinoma With Hypoalbuminemia

This study is comparing two treatments for small liver tumors called hepatocellular carcinoma (liver cancer) in patients who also have low albumin levels (a protein in the blood that indicates liver function). The two treatments being compared are microwave ablation (a heat-based procedure to destroy the tumor) and Y-90 radioembolization (delivering targeted radiation through tiny beads inserted into the blood vessels feeding the tumor). **You may be eligible if...** - You have been diagnosed with liver cancer according to standard imaging guidelines - Your tumor is small (3 cm or less), solitary, and cannot be surgically removed - You have low albumin levels (below 3.4 g/dL) - You have not received any prior liver treatment for this cancer - Your liver function and overall health are adequate **You may NOT be eligible if...** - You are pregnant - You have another active cancer at the same time Talk to your doctor to see if this trial is right for you.