RecruitingNCT05955456

Detecting EARLY Heart Failure in Greater Manchester

Detecting EARLY Heart Failure in Greater Manchester (EARLY-HF)

Sponsor

Manchester University NHS Foundation Trust

Enrollment

600 participants

Start Date

Oct 9, 2023

Study Type

OBSERVATIONAL

Conditions

Heart Failure

Summary

Heart failure represents a growing public health problem within the UK and particularly within the North West of England. A major challenge is that heart failure is currently diagnosed too late. The researchers have previously developed a risk calculator that accurately identifies individuals at risk of heart failure admission or death before they have developed heart failure. Most risk calculators are never implemented into clinical practice. The researchers will l perform a pilot study to evaluate the risk calculator within primary care in Greater Manchester.

Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is looking for early signs of heart failure in people in Greater Manchester who have multiple common health conditions. Researchers will use a special heart MRI scan to detect heart failure before it becomes severe. **You may be eligible if...** - You are 50 years or older - You have two or more of the following: type 2 diabetes, COPD (a lung disease), coronary heart disease, atrial fibrillation (irregular heartbeat), high blood pressure, moderate kidney disease (stage 3), or a BMI of 30 or higher (obese range) **You may NOT be eligible if...** - You have already been diagnosed with heart failure, a significant heart muscle disease, moderate-to-severe heart valve disease, or congenital heart disease - You have had a heart transplant - You have a pacemaker, metal implants in your eyes, or severe claustrophobia that prevents MRI scanning - You are pregnant or breastfeeding - You have severe kidney disease (very low kidney function) - You have had a severe allergic reaction to MRI contrast dye Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNo intervention

No intervention is applied to participants. The risk calculator score is not released to the participants or care providers. Participants are followed up for risk calculator accuracy and recalibration.