RecruitingNCT05963126

Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients

Modified Urine Fetuin A as a Predictor of Deterioration of Renal Function in Patients With Resistant and Non-resistant Hypertension

Sponsor

University Hospital Ostrava

Enrollment

200 participants

Start Date

Jul 1, 2023

Study Type

OBSERVATIONAL

Conditions

Arterial Hypertension

Summary

Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin/creatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment. Modified human urine Fetuin A (urine Fetuin A) with specific modification in urine (Fetuin A) can earlier predict the progression of kidney disease in patients with diabetes. Studies evaluating urine Fetuin A in hypertonic patients are still lacking.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether a blood protein called fetuin-A can predict kidney function decline in people with high blood pressure (hypertension). The goal is to find early warning signs of kidney damage before it becomes serious. **You may be eligible if...** - You have been diagnosed with high blood pressure and are taking at least one blood pressure medication - You are willing to have blood tests and follow-up kidney function checks **You may NOT be eligible if...** - You have diabetes (any type) - Your blood pressure is severely uncontrolled - You already have advanced kidney disease - You have conditions that affect protein levels in the blood, such as severe liver disease or chronic inflammatory conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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