RecruitingNCT05971836

The Molecular Basis of Inherited Reproductive Disorders


Sponsor

Stephanie B. Seminara, MD

Enrollment

600 participants

Start Date

Jan 21, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to learn more about the genes that control puberty and reproduction in humans.


Eligibility

Min Age: 1 Year

Inclusion Criteria7

  • Participants must belong to one of the following categories:
  • Failure to go through a normal, age-appropriate, spontaneous puberty and low sex steroid levels in the setting of low/normal gonadotropins or,
  • Abnormally early development of puberty or,
  • Normal puberty with subsequent development of low gonadotropin levels or,
  • Evidence of a reproductive disorder with high gonadotropin levels or,
  • Pre-pubertal individuals with features suggestive of hypogonadotropic hypogonadism or,
  • Affected and unaffected family members of individuals that fit criteria above

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Locations(1)

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT05971836


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