RecruitingNot ApplicableNCT05974995

Robotic-assisted Versus Conventional Laparoscopic Surgery in Obese Patients With Early Endometrial Cancer

Robotic-assisted Versus Conventional Laparoscopic Surgery in the Management of Obese Patients With Early Endometrial Cancer in the Sentinel Lymph Node Era: a Randomized Controlled Study


Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Enrollment

566 participants

Start Date

Sep 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Data across literature suggest that robotic surgery may offer benefit specifically in patient with morbid obesity with endometrial cancer, but to date no randomized trials have been conducted to confirm these observations. This randomized controlled multicentric trial aims to evaluate the most appropriate minimally invasive surgical approach in morbidly obese (BMI \>= 30) patients with endometrial carcinoma.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 75 Years

Inclusion Criteria7

  • BMI \>=30
  • Age \> 18
  • Histologically confirmed endometrioid endometrial cancer
  • Clinical early stage (stage I)
  • No contraindication for minimally invasive surgery
  • ASA\<4
  • Written informed consent.

Exclusion Criteria4

  • High probability of laparotomy related to uterine volume (US estimated weight \>250 g)
  • Concomitant pelvic disease, or anatomical characteristics of the patient
  • (Use of uterine manipulator)
  • Age \>75 years

Interventions

PROCEDURERobot-assisted surgery

Total hysterectomy with bilateral salpingo-oophorectomy and lymphnodes staging using DaVinci Xi

PROCEDURELaparoscopic surgery

Total hysterectomy with bilateral salpingo-oophorectomy and lymph nodes staging using standard laparoscopic approach


Locations(1)

Policlinico Gemelli IRCCS

Rome, Italy

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NCT05974995


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