RecruitingNot ApplicableNCT05976945

Imagery Rescripting as Treatment for Depression

Imagery Rescripting as a Stand-alone Treatment for Depression: a Pilot Study.


Sponsor

University of Amsterdam

Enrollment

10 participants

Start Date

Aug 10, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this multiple baseline case series study is to test Imagery Rescripting in depression. The main question\[s\] it aims to answer are: * does Imagery Rescripting lead to a reduction of depression and of believability of negative beliefs held by the participants? * does Imagery Rescripting also leads to reductions in worrying and brooding? * Participants will wait for 6-10 weeks (to assess time effects without treatment), followed by 5 weekly preparation sessions, 8-12 weekly Imagery Rescripting sessions, and 5 weeks post-treatment. * Participants will rate the believability of 3-5 core dysfunctional beliefs related to their depression as well as 2 items assessing depression severity on a weekly basis. In addition, they will fill out more extensive questionnaires on depression, worry and brooding before each phase, as well as at 5 weeks post-treatment, and 6 and 12 months follow-up.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a psychological technique called imagery rescripting as a treatment for depression. Imagery rescripting involves revisiting distressing memories and changing the mental "image" of how they play out, to reduce their emotional impact. **You may be eligible if...** - You are 18–65 years old - You have been diagnosed with major depressive disorder (MDD) according to clinical interview - Your depression is at least moderate in severity (BDI-II score of 20 or higher) - You speak Dutch or English as your first language (or are fluent enough to receive therapy in these languages) **You may NOT be eligible if...** - You have bipolar I disorder with a manic episode in the past year - You have a psychotic disorder - You have active suicidal intent that requires urgent safety management Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALImagery Rescripting

In Imagery Rescripting patients imagine a different sequence of events matching their needs better than what actually happened in traumatic and other adverse (childhood) experiences.


Locations(1)

Academic Center for Trauma and Personality ACTP

Amsterdam, Netherlands

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NCT05976945


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