RecruitingNot ApplicableNCT05980793

Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)

Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS), a Randomized Controlled Trial

Sponsor

Karolinska Institutet

Enrollment

90 participants

Start Date

Sep 25, 2023

Study Type

INTERVENTIONAL

Conditions

Surgery Osteoarthritis Finger

Summary

The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are: * Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise). Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age ≥ 18 years.
Chronic symptomatic osteoarthritis in the PIP-joint.
Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957).
Clinical signs of PIP-joint arthritis.

Exclusion Criteria4

Inflammatory arthritis.
Ongoing infection in the hand.
Inability to co-operate with the follow-up protocol.
Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment.

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