Surgery Clinical Trials

1,342 recruitingLast updated: June 17, 2026

There are 1,342 actively recruiting surgery clinical trials across 75 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1, Early Phase 1. Top locations include Beijing, Beijing Municipality, China, Guangzhou, Guangdong, China, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Surgery Trials at a Glance

1,342 actively recruiting trials for surgery are listed on ClinicalTrialsFinder across 6 cities in 75 countries. The largest study group is Not Applicable with 638 trials, with the heaviest enrollment activity in Beijing, Guangzhou, and New York. Lead sponsors running surgery studies include Centre Hospitalier Universitaire, Amiens, Cairo University, and Assistance Publique - Hôpitaux de Paris.

Treatments under study

About Surgery Clinical Trials

Looking for clinical trials for Surgery? There are currently 254 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Surgery trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Surgery clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,342 trials

Recruiting
Not Applicable

Improvement of Gait by Spinal Stimulation in Patients With Postoperative Chronic Lumbosciatalgia: Pilot Study (GaitStim)

Failed Back Surgery Syndrome
Centre Hospitalier Universitaire de Nice36 enrolled1 locationNCT05857696
Recruiting
Not Applicable

Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block

Pain, PostoperativeThoracic Surgery, Video-assistedMultimodal Analgesia+2 more
Ankara City Hospital Bilkent90 enrolled1 locationNCT07650877
Recruiting
Not Applicable

Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery

Video-assisted Thoracoscopic Surgery (VATS)SegmentectomyWedge Resection+3 more
Beijing Tiantan Hospital100 enrolled1 locationNCT07603921
Recruiting
Phase 4

The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response

surgical stress responseThyroid CancerThyroid and Parathyroid Surgery+1 more
University Hospital Dubrava48 enrolled1 locationNCT07600580
Recruiting
Not Applicable

Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival

Intraoperative hypothermiaCancer SurgeryPostoperative Delirium+2 more
Peking University First Hospital3,992 enrolled36 locationsNCT06256354
Recruiting

Prediction Model for MINS After Major Hepatobiliary Surgery

Postoperative ComplicationsLiver NeoplasmMyocardial Injury After Noncardiac Surgery (MINS)+1 more
Beijing Tsinghua Chang Gung Hospital1,800 enrolled6 locationsNCT07335042
Recruiting
Not Applicable

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

Reconstruction SurgeryAirway RemodelingTrachea Diseases
National Taiwan University Hospital10 enrolled2 locationsNCT06935110
Recruiting
Not Applicable

Comparison of Cumulative Opioid Consumption Between Variable-Rate Feedback Infusion and Fixed-Rate Basal Infusion Modes of Intravenous PCA Following Mixed Surgery

SurgeryPain ManagementPatient-controlled Analgesia+1 more
Beijing Tiantan Hospital1,170 enrolled1 locationNCT07361822
Recruiting
Phase 2

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Acute Kidney InjuryCardiac Surgery
Arch Biopartners Inc.240 enrolled9 locationsNCT05879432
Recruiting
Not Applicable

Postoperative Electrical Muscle Stimulation Two

Colorectal, CancerSurgeryMuscle Atrophy+1 more
University of Nottingham45 enrolled1 locationNCT06964438
Recruiting
Not Applicable

Efficacy of Written Versus Video Patient Education Materials for Postmastectomy Breast Reconstruction

Breast Surgery
University of California, San Francisco100 enrolled1 locationNCT07602374
Recruiting
Not Applicable

Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections

SurgeryLight; Therapy, ComplicationsNasal Disease
Guy's and St Thomas' NHS Foundation Trust80 enrolled1 locationNCT06731881
Recruiting
Not Applicable

Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery

Obesity and OverweightBariatric SurgeryObesity, Morbid+4 more
Centre Hospitalier Metropole Savoie165 enrolled1 locationNCT06951893
Recruiting
Not Applicable

COmbined pLaTelet and eRythrocyte AutotransfusioN During Cardiac surgEry (COLTRANE) Trial

On-pump Cardiac SurgeryHigh Risk for BleedingAutotransfusion
University Hospital, Bordeaux570 enrolled10 locationsNCT06425614
Recruiting
Not Applicable

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

knee arthropathySurgeryKnee Osteoarthritis
The Cleveland Clinic300 enrolled1 locationNCT06298721
Recruiting
Not Applicable

Implementing Surgery School Prehabilitation Using Telehealth

Adults Waiting to Undergo Lung Cancer or Major Abdominal, Open or Video Assisted Cancer Surgery
University of Melbourne515 enrolled9 locationsNCT06631872
Recruiting
Not Applicable

The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery

Impacted Mandibular Third MolarOral Surgerypostoperative morbidity
Recep Tayyip Erdogan University148 enrolled1 locationNCT07198282
Recruiting
Not Applicable

VR-Based Cognitive Stimulation Games for Delirium Prevention

SurgeryDeliriumDelirium - Postoperative
The Methodist Hospital Research Institute90 enrolled2 locationsNCT07641153
Recruiting
Phase 3

Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries

Sphenopalatine BlockTurbinate Surgery
Ain Shams University50 enrolled1 locationNCT07299630
Recruiting

Construction and Clinical Validation of a Predictive Model for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma Based on Whole-Slide Digital Pathological Images and Deep Learning

Liver surgeryHepatocellular Carcinoma (HCC)Adjuvant Chemoradiotherapy+3 more
Second Affiliated Hospital, School of Medicine, Zhejiang University11,000 enrolled1 locationNCT07417800