Surgery Clinical Trials

1,317 recruitingLast updated: June 6, 2026

There are 1,317 actively recruiting surgery clinical trials across 75 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1, Early Phase 1. Top locations include Beijing, Beijing Municipality, China, Guangzhou, Guangdong, China, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Surgery Trials at a Glance

1,317 actively recruiting trials for surgery are listed on ClinicalTrialsFinder across 6 cities in 75 countries. The largest study group is Not Applicable with 622 trials, with the heaviest enrollment activity in Beijing, Guangzhou, and New York. Lead sponsors running surgery studies include Cairo University, Centre Hospitalier Universitaire, Amiens, and Assistance Publique - Hôpitaux de Paris.

Treatments under study

About Surgery Clinical Trials

Looking for clinical trials for Surgery? There are currently 251 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Surgery trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Surgery clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,317 trials

Recruiting
Phase 3

Suzetrigine in Total Hip Arthroplasty

Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting

Fascial Plane Blocks In Cardiac Surgery

Regional AnaesthesiaCardiovascular Surgerypostoperative analgesia
Antalya Health Sciences University90 enrolled1 locationNCT07622823
Recruiting
Not Applicable

A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine

Cardiac Surgery associated Acute kidney injury
Bayer200 enrolled4 locationsNCT06772025
Recruiting
Not Applicable

Prehabilitation for Ovarian Cancer Patients

ExerciseOvarian CancerPrehabilitation+4 more
Nova Scotia Health Authority108 enrolled1 locationNCT05364879
Recruiting
Not Applicable

Endoscopic Video-Assisted Nipple-Sparing Mastectomy

Breast CancerBreast SurgeryEndoscopic Video-assisted Nipple-sparing Mastectomy
European Institute of Oncology10 enrolled1 locationNCT07579117
Recruiting
Not Applicable

Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction

Breast ReconstructionDIEP Flap Breast ReconstructionBreast Cancer, Breast Neoplasms+1 more
Beaumont Hospital250 enrolled1 locationNCT07230535
Recruiting
Not Applicable

Non-interventional Study Exploring the Composition of the Valvular Microbiota of Patients Undergoing Cardiac Surgery

MicrobiotaCardiac SurgeryValvulopathy
University Hospital, Toulouse200 enrolled1 locationNCT07075601
Recruiting
Phase 2

Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS

Renal StonesRetrograde Intrarenal SurgeryUreteral Access Sheath Placement
Beni-Suef University322 enrolled3 locationsNCT07623876
Recruiting
Not Applicable

Rehabilitation With Empowered STrategies to Optimize REcovery

Lumbar Spine SurgeryLumbar Spine Degenerative Changes
Vanderbilt University Medical Center100 enrolled4 locationsNCT07406997
Recruiting
Not Applicable

Comparison of Analgesic Effects of ACB Versus ACB Combined With BiFeS Block in Meniscopathy Surgery

Pain ManagementPeripheral Nerve BlockMeniscopathy Surgery
Ankara Etlik City Hospital135 enrolled1 locationNCT07603323
Recruiting
Not Applicable

Feasibility of a Co-designed Mobility Intervention After Hip Fracture Surgery

hip fracture surgeryMobility LimitationPostoperative Rehabilitation
Hvidovre University Hospital25 enrolled1 locationNCT07561164
Recruiting
Phase 3

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

Cardiac SurgeryCardiopulmonary BypassNitric Oxide+1 more
Xijing Hospital3,650 enrolled3 locationsNCT06702553
Recruiting
Phase 3

Levetiracetam for Seizure Prevention After Brain Tumor Surgery

Postoperative Seizures After Brain Tumor Surgery
Beijing Tiantan Hospital558 enrolled1 locationNCT07239115
Recruiting
Not Applicable

Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot Trial

SurgeryQuality of LifePain, Postoperative+5 more
CHU de Quebec-Universite Laval100 enrolled3 locationsNCT06884540
Recruiting

Mechanical Ventilation in Surgical Patients

SurgeryPostoperative ComplicationsVentilator Lung
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria10,000 enrolled1 locationNCT06296277
Recruiting
Not Applicable

Bariatric Surgery for the Reduction of cArdioVascular Events Randomized Controlled Trial

Cardiovascular ComplicationBariatric Surgery Candidate
Population Health Research Institute700 enrolled1 locationNCT05531474
Recruiting
Not Applicable

External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery

Abdominal surgeryPostoperative Pain
Jun Zhang78 enrolled1 locationNCT07331441
Recruiting
Phase 2

A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery

Pain After Surgery
Haisco Pharmaceutical Group Co., Ltd.200 enrolled2 locationsNCT07533786
Recruiting

Low-Flow Anesthesia and Open-Heart Surgery

Open-heart surgeryHemodynamicsLow-Flow Anesthesia
Çağrı Özdemir80 enrolled1 locationNCT07040735
Recruiting

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Open GI Surgery
University of Minnesota300 enrolled1 locationNCT06300892