GpCRC Pediatric Gastroparesis Registry 2

Exclusion Criteria18

• Inability to comply with or complete the scintigraphic gastric emptying test (including allergy to eggs)
• Pregnancy
• Autism spectrum disorder, significant developmental delay, psychosis (because of inability to complete questionnaires)
• Use of narcotic analgesics greater than three days per week.
• Presence of conditions associated with GI mucosal disease (e.g., inflammatory bowel disease, known eosinophilic gastroenteritis or eosinophilic esophagitis, gastric ulcer, peptic ulcer, celiac disease)
• Presence of any other condition that could case delayed gastric emptying
• Gastrointestinal construction confirmed by upper endoscopy (EGD), upper gastrointestinal series (UGI), or abdominal CT
• Primary neurological conditions that can cause nausea and vomiting such as increased intracranial pressure, space occupying or inflammatory/infectious legions
• Acute or chronic renal failure (abnormal creatinine for age) and /or on hemodialysis or peritoneal dialysis
• Acute liver failure
• Advanced liver disease (features of portal hypertension)
• Clinically significant congenital heart disease (i.e., vaginal injury during cardiac repair)
• History of esophageal, gastric or bowel surgery.
• Metabolic disease including mitochondrial disease and inborn errors of metabolism
• Chronic lung disease (including cystic fibrosis)
• A serious chronic medical condition (e.g., inflammatory bowel disease)
• Use of medications that can affect motility during the gastric emptying study
• Any other condition, which in the option of the investigator, could explain the symptoms or could interfere with study requirements.