Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer

This study tests whether a drug called atovaquone — originally used to treat malaria and other infections — can help treat a type of ovarian cancer that has stopped responding to standard platinum-based chemotherapy. **You may be eligible if...** - You have high-grade serous ovarian cancer that has come back or progressed within 6 months of your last platinum-based chemotherapy (this is called platinum-resistant) - You are in good enough health to participate (ECOG performance status 0 or 1, meaning you can carry out normal daily activities) - You are 18 years or older - You may have had any number of prior treatments **You may NOT be eligible if...** - You are under 18 years old - You are pregnant or breastfeeding - You are currently incarcerated - You are unable to provide consent or make your own medical decisions Talk to your doctor to see if this trial is right for you.