RecruitingNCT06001450

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

PLANET: Exploring the Role of Plastics and Toxins in Intestinal Inflammation

Sponsor

Icahn School of Medicine at Mount Sinai

Enrollment

46 participants

Start Date

Aug 15, 2023

Study Type

OBSERVATIONAL

Conditions

Pregnancy Inflammatory Bowel Disease Crohns Disease

Summary

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as other diseases. With this information, the researchers hope to characterize better the role of environmental pollutants on IBD and develop novel strategies towards prevention.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

The ability to sign and date an informed consent form
Be pregnant, or wishing to become pregnant in the near future and enroll the infant that the individual is pregnant with
Aged 18 or older
English-speaking (this observational study uses non-validated questionnaires that are only available in English)
Of any ethnicity
Be a spouse, related household member (sibling, parent, etc.) or a child of an enrolled pregnant person

Exclusion Criteria2

Individuals who are unable to give informed consent
Be diagnosed with a pregnancy complication, such as intrauterine fetal demise/stillbirth, preeclampsia, hyperemesis gravidarum, or have an active infection, including chorioamnionitis or sepsis.