RecruitingPhase 2Phase 3NCT06001918

Nectero EAST System Clinical Study

Randomized Controlled Clinical Trial (RCT) of the Nectero EAST System for Small to Mid-Sized Abdominal Aortic Aneurysms (AAA) StaBiLization: Evaluation of Efficacy.


Sponsor

Nectero Medical, Inc.

Enrollment

400 participants

Start Date

Oct 25, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this randomized clinical trial is to treat patients with small to mid-sized abdominal aortic aneurysms (AAA), maximum diameter of 3.5 cm to 5.0 cm, using a locally delivered, single-dose endovascular treatment. The main question the study aims to answer is to demonstrate efficacy of the product for stabilization of these small to mid-sized AAA.The study will compare the treatment group to the typical standard of care for these patients, surveillance. All subjects will be followed at designated intervals at 30/60 days, 6, 12, 18 and 24 months with continued follow-up annually for up to 5 years.


Eligibility

Min Age: 21 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nectero EAST System for people with abdominal aortic aneurysm. The study is currently recruiting participants at 39 locations. People eligible for this study include aged 21 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNectero EAST System

Treated subjects will undergo an endovascular procedure with the Nectero EAST system and receive the Stabilizer Infusion Solution (drug) within 30 days of the study eligibility by CT scan as a one-time local delivery of the drug.


Locations(39)

Honor Health Scottsdale Shea Medical Center

Scottsdale, Arizona, United States

University of Colorado

Aurora, Colorado, United States

Medstar Washington Hospital Center

Washington D.C., District of Columbia, United States

Prime Vascular Institute

Delray Beach, Florida, United States

Medical College of Georgia

Augusta, Georgia, United States

University of Chicago

Chicago, Illinois, United States

MaineMed Vascular Surgery

Scarborough, Maine, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

University of Massachusetts

Worcester, Massachusetts, United States

Beaumont Health

Royal Oak, Michigan, United States

Washington University School of Medicine

St Louis, Missouri, United States

University of Nebraska Medical Center

Omaha, Nebraska, United States

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, United States

University of Rochester

Rochester, New York, United States

Stony Brook Medicine

Stony Brook, New York, United States

Duke University Medical Center

Durham, North Carolina, United States

The Christ Hospital

Cincinnati, Ohio, United States

University Hospitals Cleveland

Cleveland, Ohio, United States

Cleveland Clinic

Cleveland, Ohio, United States

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States

Ohio Health Riverside

Columbus, Ohio, United States

Oklahoma Heart Institute

Tulsa, Oklahoma, United States

Portland VA Medical Center

Portland, Oregon, United States

St. Luke's University Health Network

Bethlehem, Pennsylvania, United States

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Jefferson Clinical Research Institute

Philadelphia, Pennsylvania, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Prisma Health

Greenville, South Carolina, United States

North Central Heart - A Division of Avera Heart Hospital

Sioux Falls, South Dakota, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Houston Healthcare

Houston, Texas, United States

Baylor Scott & White Medical Center

Plano, Texas, United States

University of Utah Hospital

Salt Lake City, Utah, United States

Inova Fairfax Medical Campus Inova Health Systems

Fairfax, Virginia, United States

University of Washington at Harborview Medical Center

Seattle, Washington, United States

Bellin Memorial Hospital

Green Bay, Wisconsin, United States

Prince of Wales Private Hospital- POW Vascular Institute

Randwick, New South Wales, Australia

Auckland City Hospital

Auckland, New Zealand

View Full Details on ClinicalTrials.gov

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NCT06001918


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