Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project

This pilot study is testing whether a blood-thinning medication (enoxaparin/low molecular weight heparin) can help prevent complications in pregnant women who had a bad pregnancy outcome previously — such as premature birth, preeclampsia, or stillbirth — and whose placenta showed signs of poor blood flow. **You may be eligible if:** - You had a prior pregnancy complication (preterm birth, preeclampsia with severe features, low-birth-weight baby, or stillbirth) - Your previous placenta showed signs of poor blood supply (maternal vascular malperfusion) - You are currently pregnant with a single baby at less than 17 weeks **You may NOT be eligible if:** - You are already planned to take blood thinners in this pregnancy - Your baby has a known major birth defect - You are allergic to heparin or pork products, or have had a reaction to enoxaparin - You have chronic kidney disease, chronic liver disease, a low platelet count, or a mechanical heart valve Talk to your doctor to see if this trial is right for you.