RecruitingPhase 1NCT06005038

CogT pSOPT Intervention Study

Personalized Engine for Speed of Information Processing


Sponsor

Stanford University

Enrollment

50 participants

Start Date

Jan 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

(JUSTIFICATION: This is the R33 stage of an NIH funded R21/R33 study. R21 stage (IRB-61727) was focused on intervention development; R33 stage will focus on pilot testing the effect of the intervention. The R21 phase was not considered a NIH defined clinical trial; R33 will be considered a NIH defined clinical trial) The purpose is to develop and test the effect of a "personalized" computer-based cognitive training program. The personalized program tailors the difficulty of the training tasks using a participant's biofeedback (i.e., heart rate) and cognitive performance. Such a personalization will ensure that the participant can perform at his/her ideal training capacity. Participants will be randomized into one of 2 groups and each group will play a different version of computerized training game and have ECG collected to allow subject blinding.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called MLA and a behavioral approach called pSOPT for people with mild cognitive impairment and subjective cognitive impairment. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALpSOPT

computerized cognitive training practicing speed of processing, the difficulty will be adjusted based on real-time monitored RMSSD (parasympathetic nervous system signals)

BEHAVIORALMLA

computerized mental leisure activities on cross-word puzzle, Sudoku, and solitaire; ECG will also be applied.


Locations(1)

CogT Lab, Stanford University

Palo Alto, California, United States

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NCT06005038


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