A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer

This is a first-in-human study testing a new cancer drug called TORL-4-500 in patients with advanced solid tumors (cancers that have spread and haven't responded to other treatments). **You may be eligible if:** - You have an advanced solid tumor (any type) - You have at least one measurable tumor on imaging - You are in good general health (ECOG performance status 0–1) - Your organs (liver, kidneys, blood) are functioning well **You may NOT be eligible if:** - You have active or growing brain metastases - You have had another cancer within the past 3 years (with some exceptions) - You have had certain cancer treatments within the past 2–4 weeks - You have a history of serious heart disease, myelodysplastic syndrome, or AML - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.