RecruitingNCT06007248

Disease Characteristics of IR-CAD: a Case-control Study

Disease Characteristics of Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Case-control Study

Sponsor

Peking Union Medical College Hospital

Enrollment

30 participants

Start Date

Nov 2, 2023

Study Type

OBSERVATIONAL

Conditions

Coronary artery stenosis Inflammation Coronary Artery Disease Inflammatory Disease Coronary Artery Disease Progression Coronary Artery Restenosis Inflammation Vascular

Summary

The present case-control study is designed to investigate the disease characteristics of IR-CAD by comparing the demographics, clinical features, lab results, imaging findings, and prior treatment between 20 patients with IR-CAD and 10 patients with AS-CAD.

Eligibility

Min Age: 45 YearsMax Age: 64 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Protocol-defined Examinations for people with coronary artery disease, coronary artery disease progression, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 45 Years to 64 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTProtocol-defined Examinations

Lab tests (blood and urine and stool routine tests, hepatic and renal and thyroid function tests, tests for metabolic markers, tests for cardiac biomarkers, thrombosis-related tests, rheumatology tests, tests for inflammation markers), electrocardiography, echocardiography, Birmingham Vasculitis Activity Score (BVAS-3), 6-minute walk test, 1-minute squat test, vascular ultrasound, fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT), coronary angiography, optical coherence tomography (OCT), tests for exploratory biomarkers.