Predictive Value of Serum and Tissue Molecular Markers and Imaging Features in the Invasiveness and Prognosis of Pituitary Neuroendocrine Tumors

This study aims to find blood markers and imaging features that can predict how aggressive a pituitary tumor (a growth in the small gland at the base of the brain) will be and how patients will do after treatment. **You may be eligible if...** - You have been diagnosed with a pituitary tumor confirmed by imaging and hormone testing **You may NOT be eligible if...** - Your tumor has been diagnosed as pituitary cancer (not benign adenoma) - You have already received radiation, chemotherapy, or immunotherapy - You have a known genetic syndrome causing hormone overproduction (e.g., MEN1) - You have an ectopic (outside the pituitary) neuroendocrine tumor - You had major surgery within the past month or pituitary surgery within 3 months - You have a hormone crisis, severe diabetes, uncontrolled blood pressure, severe organ damage, or serious psychiatric illness Talk to your doctor to see if this trial is right for you.