RecruitingPhase 2NCT06017141

Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study

VIVA: Volatile or IV Anesthesia for Cancer

Sponsor

University of Kansas Medical Center

Enrollment

80 participants

Start Date

May 22, 2023

Study Type

INTERVENTIONAL

Conditions

Colon Adenocarcinoma

Summary

This trial evaluates how inhalational anesthesia (drawn in through the lungs) and total intravenous anesthesia (TIVA) (through a needle in a vein in the arm) change the body's ability to recover from surgery or whether they impact the immune system immediately after surgery in patients with colon cancer. It is unknown whether these types of anesthesia change recovery from surgery or change the chances cancer comes back following surgery. This study may help researchers learn how different types of anesthesia affect recovery from colon cancer surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (called VIVA) compares two common types of anesthesia — inhaled gas anesthesia versus intravenous (IV) propofol anesthesia — to see if one leads to better long-term outcomes for patients having colon cancer surgery. **You may be eligible if...** - You are 18 or older - You are scheduled for surgery to remove a confirmed colon cancer (adenocarcinoma) - You are medically fit for the surgery - You are able to complete study questionnaires **You may NOT be eligible if...** - You have rectal cancer (not colon cancer) - You are currently enrolled in another treatment clinical trial - You are a prisoner - You are allergic to eggs, soy, or soybeans (which are in propofol) - You or a close family member have a history of malignant hyperthermia (a rare reaction to inhaled anesthetics) - You have inflammatory bowel disease or need removal of multiple organs at once Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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