RecruitingNCT06023225
Sex Hormones, Postoperative Pain and Opioid Use
Relationship Between Sex Hormones, Postoperative Pain and Opioid Use: the Role of Immune Factors
Sponsor
Washington University School of Medicine
Enrollment
210 participants
Start Date
Sep 1, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use. Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors
Eligibility
Sex: FEMALEMin Age: 11 YearsMax Age: 16 Years
Inclusion Criteria1
- Pediatric female patients between the ages 11-16 undergoing an orthopedic (trauma and non-trauma) surgical procedure involving a long bone or joint, or the spine, English speaking
Exclusion Criteria1
- Pregnancy; Diagnosis of chronic pain, Psychiatric, developmental or neurological disorders, Disorders that are associated with pubertal maturation (e.g., precocious puberty).
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Interventions
BEHAVIORALPain
Postoperative pain levels
BEHAVIORALOpioid use
Postoperative opioid use
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06023225
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