RecruitingPhase 3NCT06031181

Sublobar Resection for Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section (ECTOP-1019)

Sublobar Resection for Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section: a Single-arm, Multi-center, Phase III Trial

Sponsor

Fudan University

Enrollment

390 participants

Start Date

Mar 31, 2023

Study Type

INTERVENTIONAL

Conditions

Lung Adenocarcinoma Frozen Section Sublobar Resection

Summary

This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1019. The goal of this clinical trial is to confirm the therapeutic effect of sublobar resection for AIS/MIA diagnosed by intraoperative frozen section.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria8

Patients who sign the informed consent form and are willing to complete the study according to the plan;
Aged from 18 to 80 years old;
ECOG equals 0 or 1;
Not receiving lung cancer surgery before;
Resectable peripheral cT1N0M0 tumors;
Single lung nodules with ground-glass dominant or pure ground-glass on CT, or multiple lung nodules with the major lesion being the aforementioned nodules;
Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section
Not receiving chemotherapy or radiotherapy before.

Exclusion Criteria5

Not cT1N0M0;
Cannot be completely resected by sublobar resection;
Invasive lung adenocarcinoma or not lung adenocarcinoma diagnosed cytologically or pathologically;
Receiving lung cancer surgery before;
Receiving radiotherapy or chemotherapy.