Feasibility and Colorectal Benefits of Pulses Supplementation
Feasibility of Pulses Supplementation in Healthy Adults: A Feeding Study
University of California, Davis
25 participants
Oct 27, 2023
INTERVENTIONAL
Conditions
Summary
Beans are a forgotten staple food that shows promise in improving health. The goal of this study is to look at how bean supplementation affects metabolic and bowel health. In the long-term, the investigators believe this research will lead to a better understanding of the impact of beans on bowel health. The investigators also hope that this research study will help us understand ways to improve human diet and prevent colon cancer in the future.
Eligibility
Inclusion Criteria11
- Inclusions:
- 30-80 years-old
- Overweight or obesity (body mass index ≥ 25 kg/m2)
- Planned for a standard of care colonoscopy for colon cancer screening
- Exclusions:
- Intolerance to a bean or high bean consumer based on a screening survey
- Pregnancy or actively planning to get pregnant
- Any active gastrointestinal disease resulting in disturbed gut function or malabsorption (e.g., chronic diarrhea or inflammatory bowel disease)
- Current or history of any malignancy in the past 10 years.
- Chronic use of opioids, anti-inflammatory drugs, antibiotics, prebiotics, or probiotics within 1 month of study endpoints
- History of a significant systemic condition (e.g., heart disease, chronic kidney disease, liver dysfunction or immune suppression), or abnormal laboratory markers (e.g., abnormal liver enzymes, creatinine, clotting factors, or low platelets count). The severity of the intolerance to fiber/ the medical conditions/lab markers and eligibility will be defined after the careful interview of the patient/review of the medical records by Dr. Hussan)
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Interventions
0.5 cup of Bush's Best Cannellini Beans, three times per day before meals blended into a smoothie. If interested and depending on tolerance, participants will also have the opportunity to gradually increase the bean smoothie to a maximum of 1 cup three times per day before meals during the last week of the two-week bean smoothie intervention. If patient cannot not tolerate 1.5 cup of canned cannellini bean, we will reduce per tolerance or offer the option of choosing a bean-based flour (100 gram/day, 23% fiber from Archer Daniels Midland)
Usual diet without adding the bean smoothie
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06032104