RecruitingNot ApplicableNCT06039644

To Evaluate the Clinical Efficacy of Probiotics in Patients With the Breast Cancer

To Evaluate the Efficacy of Probiotics in Improvement and Prevention of Chemotherapy Associated Side Effectes in Patients With the Breast Cancer

Sponsor

GenMont Biotech Incorporation

Enrollment

100 participants

Start Date

Apr 8, 2024

Study Type

INTERVENTIONAL

Conditions

Breast Cancer

Summary

Chemotherapy-associated side-effects would affect therapeutic effect, quality of life, and cause permanent harm to breast cancer patients. This study is designed to explore after consumption of probiotics of lactobacillus composite strain powder sachets for 6 months in breast cancer chemotherapy, and whether the improvement of meliorate the side effects, further assists patients completing the chemotherapy.

Eligibility

Min Age: 20 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether taking probiotics (beneficial gut bacteria) during chemotherapy can reduce side effects and improve overall health in patients with breast cancer undergoing anthracycline- and taxane-based chemotherapy. **You may be eligible if...** - You have stage I–III breast cancer - You are receiving chemotherapy that includes anthracyclines (e.g., doxorubicin) and taxanes (e.g., paclitaxel) - You are 20–80 years old - Your BMI is above 18 (not severely underweight) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have had weight-loss surgery or have conditions like Crohn's disease, celiac disease, or significant bowel removal - You have a severe allergy to soybeans or peanuts - You are under 20 or over 80 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTProbiotic

Three-strain probiotic supplement includes Lactobacillus reuteri GMNL-89 (alive), Lactobacillus plantarum GMNL-141 (alive) and Lactobacillus paracasei GMNL-133 (alive).

OTHERPlacebo

Same additives to Probiotic group but replace probiotics with corn starch and Maltodextrin.

Locations(1)

Mackay Memorial Hospital

Taipei, Taiwan

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NCT06039644

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