Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
Chung Shan Medical University
100 participants
Dec 26, 2023
INTERVENTIONAL
Conditions
Summary
The aim of the study is to investigate the effect of coenzyme Q10 supplementation (150 mg/b.i.d, 300 mg/d, 12 weeks) on coenzyme Q10, glucose parameters, BDNF, myokines, and cognitive function in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients who combined with hyperglycemia but without sarcopenia, or with hyperglycemia and pre-sarcopenia.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
300 mg/day (150mg/b.i.d)
Starch, dextrin
Locations(1)
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NCT06040905