RecruitingNCT06044909

Multimodal Image Registration for Helping Laparoscopic Liver Surgery Guidance

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Enrollment

40 participants

Start Date

Sep 15, 2023

Study Type

OBSERVATIONAL

Conditions

Hepatectomy

Summary

Multimodal intraoperative minimal-invasive (laparoscopic or robotic) liver surgery images will be registered to each other. Explicitly, these are the ultrasound and laparoscope images. Once they are registered, they will reveal the hidden tumor's location to the surgeon in real time through augmented reality. The intraoperative augmentation will also be enriched with the preoperative data (e.g., CT or MRI). This will simplify minimal invasive liver surgery, improve surgical safety and accuracy. It will also shorten hospital stays and contribute to an overall better quality of life for the patient, which in return will reduce the health-care costs.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Patients undergoing hepatectomy;
Patients for whom good-quality imaging is available (CT scan and/or MRI and/or ultrasound);
Patients over 18 years of age;
Minimally invasive surgery by conventional or robot-assisted laparoscopy.

Exclusion Criteria1

Surgery by laparotomy

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Interventions

PROCEDUREMinimal invasive hepatectomy, intraoperative stage

Trocar layout is recorded by photo or diagram. The video of conventional or robot-assisted laparoscopy and intraoperative laparoscopic ultrasound images (where applicable) are recorded by the surgeon and anonymized. Depth measurements of internal structures (tumors, cysts, vascular network, anatomical landmarks) are taken using identifiable points on the surface of the liver for tumour resection.

PROCEDUREMinimal invasive hepatectomy, postoperative stage

The registration of imaging data in conventional or robot-assisted laparoscopy is performed by the scientific team using the developed registration algorithm. The data obtained from the clinical intervention will help improve the registration algorithm.

OTHERPreoperative data collection

Patient code (anonymised) + inclusion number, repeated on each page. Anonymised CT or MRI scan and date of scan. Type of cancer, planned surgery and approach (robotic or laparoscopic). Patient's age. Patient's surgical history. Toxic habits: tobacco, alcohol. Healthy liver, liver disease, cirrhosis. Anticoagulant and antiaggregant treatment.

OTHERIntraoperative data collection

Endoscope calibration. Intraoperative surgical and ultrasound images. Measurements for tumor's size and tumor's distances from liver surface and vascular vascular structures.

OTHERPostoperative data collection

Definitive anatomical pathology with the measurement of resection margins.