RecruitingPhase 3NCT07507643

A Study of Methylprednisolone in People Having Liver Surgery

A Randomized Controlled Trial of Methylprednisolone Versus Standard of Care in Patients Undergoing Major Hepatectomy

Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

750 participants

Start Date

Mar 27, 2026

Study Type

INTERVENTIONAL

Conditions

Hepatectomy

Summary

The purpose of this study is to test whether receiving methylprednisolone before surgery will reduce the side effects of having surgery, such as infections and longer hospital stays.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Methylprednisolone for people with hepatectomy. The study is currently recruiting participants at 19 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMethylprednisolone

single preoperative dose of methylprednisolone

Locations(19)

Rush University Medical Center (Data collection only)

Chicago, Illinois, United States

University of Chicago (Data Collection Only)

Chicago, Illinois, United States

Indiana University (Data Collection Only)

Indianapolis, Indiana, United States

UNIVERSITY OF IOWA (Data Collection Only)

Iowa City, Iowa, United States

University of Kentucky (Data Collection Only)

Lexington, Kentucky, United States

Henry Ford Hospital (Data collection only)

Detroit, Michigan, United States

Mayo Clinic (Data Collection Only)

Rochester, Minnesota, United States

Washington University (Data Collection Only)

St Louis, Missouri, United States

University of Nebraska Medical Center (Data Collection Only)

Omaha, Nebraska, United States

Rutgers University (Data Collection Only)

New Brunswick, New Jersey, United States

Memorial Sloan Kettering Commack (Data Collection Only)

Commack, New York, United States

Memoral Sloan Kettering Westchester (Data Collection Only)

Harrison, New York, United States

Northwell Health (Data collection only)

Manhasset, New York, United States

New York University (Data Collection Only)

New York, New York, United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States

SUNY Upstate Medical University

Syracuse, New York, United States

Duke University (Data Collection Only)

Durham, North Carolina, United States

Gundersen Lutheran Medical Foundation (Data Collection Only)

La Crosse, Wisconsin, United States

University of Wisconsin (Data Collection Only)

Madison, Wisconsin, United States

View Full Details on ClinicalTrials.gov

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NCT07507643

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