RecruitingNCT06046365

Early Diagnosis of Breast Cancer-related Lymphedema

Sponsor

Kaohsiung Veterans General Hospital.

Enrollment

300 participants

Start Date

Oct 24, 2022

Study Type

OBSERVATIONAL

Conditions

Lymphedema

Summary

This study will conduct clinical trials to explore the mechanisms behind the development of upper limb lymphedema following breast cancer surgery. The investigators will recruit patients who have undergone breast cancer surgery and utilize Indocyanine Green (ICG) lymphography and Lymphoscintigraphy to identify the locations of lymphatic blockages. Shear Wave Elastography (SWE) will be used to detect changes in tissue limb compliance. DXA body composition analysis will measure the differences in the composition ratios between edematous and normal limbs. In addition, diffusion correlation spectrometry will be employed to monitor changes in deep tissue blood flow, complemented by continuous measurements of limb circumference and other physiological parameters. The study aims to explore the interrelationships among lymphatic circulation, limb circumference, tissue compliance, and tissue blood flow rates.

Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study looks at new ways to detect arm swelling (lymphedema) early in women who have had breast cancer surgery. Lymphedema — a buildup of fluid causing swelling — is a common side effect of breast cancer treatment, and detecting it earlier may allow for better management. **You may be eligible if...** - You are a woman aged 20–80 - You are scheduled for breast cancer surgery or have already had breast cancer surgery - You do not have open wounds or significant physical limitations in the arm being measured **You may NOT be eligible if...** - You have severe cognitive problems that prevent participation - You have open wounds or other conditions in the measurement area - You have significant arm weakness or limited range of motion - You have a history of substance abuse Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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