RecruitingNot ApplicableNCT06046586

Internet-Delivered Psychological Treatment for Cancer Survivors

Randomized Factorial Trial of Internet-Delivered Psychological Treatment for Cancer Survivors With Clinically Significant Psychiatric Symptoms

Sponsor

Karolinska Institutet

Enrollment

400 participants

Start Date

Apr 10, 2025

Study Type

INTERVENTIONAL

Conditions

Cancer Survivors Depression Anxiety

Summary

Negative psychological effects of cancer are common, but cancer survivors are rarely offered structured psychological treatment. Internet-delivered treatments have shown some promise, but specific treatment components have not been empirically evaluated which means that it is not clear which therapies that should be prioritized. In this randomized factorial trial at Karolinska Institutet, Stockholm, Sweden, 400 cancer survivors with psychiatric symptoms are enrolled in variations on a 10-week therapist-guided online psychological treatment intended to address the negative psychological long-term effects of cancer. The aim is to determine the contribution of treatment components to the overall effect.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests an online psychological therapy program for cancer survivors who are experiencing anxiety, depression, or fear that their cancer might come back. The program is delivered entirely over the internet, making it accessible without needing to travel to a clinic. **You may be eligible if...** - You are a cancer survivor, at least 6 months past your main treatment - You are 18 or older - You have meaningful levels of anxiety, depression, or fear of cancer returning (based on standard questionnaires) - You live in Stockholm, Västra Götaland, or Skåne, Sweden - You are comfortable with written Swedish and have access to an internet-connected device **You may NOT be eligible if...** - You have recurring thoughts of suicide - You are currently in another psychological therapy program - You do not have internet access or sufficient Swedish language skills Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALSupport and information

Emotional and technical support. Information about the long-term effects of cancer.

BEHAVIORALBehavioral activation

Behavioral activation with existential themes and emphasis on values and relationships.

BEHAVIORALSystematic exposure with mindfulness training

Systematic exposure with mindfulness training with a focus on anxiety about health and/or death, body image, and cancer-related trauma.

BEHAVIORALPromotion of health behaviors

An overview of self-management techniques in terms of physical exercise, dietary advice, and strategies for improved sleep.

Locations(1)

Karolinska Institutet

Stockholm, Sweden

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NCT06046586

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