Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder

This study tests whether prolonged exposure therapy — a proven PTSD treatment that involves gradually confronting trauma-related memories in a safe environment — also works for patients who have both PTSD and a psychotic disorder (such as schizophrenia), a combination that is rarely treated together. **You may be eligible if...** - You are 18 or older - You have a diagnosed psychotic disorder (such as schizophrenia or affective disorder with psychosis) - You also have PTSD (with a structured interview score of 23 or higher on the CAPS-5) - You have a good understanding of German - Your medication (neuroleptic or antidepressant) has been stable for at least 4 weeks **You may NOT be eligible if...** - You have active suicidal thoughts - You have a substance dependence problem (other than nicotine or caffeine) - Your IQ is 70 or below - You are pregnant Talk to your doctor to see if this trial is right for you.