Post Traumatic Stress Disorder Clinical Trials

95 recruiting

Post Traumatic Stress Disorder Trials at a Glance

116 actively recruiting trials for post traumatic stress disorder are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 76 trials, with the heaviest enrollment activity in Houston, Boston, and San Diego. Lead sponsors running post traumatic stress disorder studies include VA Office of Research and Development, Yale University, and Karolinska Institutet.

Browse post traumatic stress disorder trials by phase

Treatments under study

About Post Traumatic Stress Disorder Clinical Trials

Looking for clinical trials for Post Traumatic Stress Disorder? There are currently 95 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Post Traumatic Stress Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Post Traumatic Stress Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 116 trials

Recruiting
Phase 3

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

PTSD - Post Traumatic Stress Disorder
Senseye, Inc.1,900 enrolled6 locationsNCT07280065
Recruiting
Not Applicable

Psychotherapy Effects on Reward Processing in PTSD

Post Traumatic Stress DisorderAnhedoniaPTSD+3 more
University of Texas at Austin120 enrolled1 locationNCT06096740
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Healthy ControlSchizophreniaPost Traumatic Stress Disorder+4 more
Yale University100 enrolled1 locationNCT01730781
Recruiting
Phase 3

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

Post Traumatic Stress Disorder
Transcend Therapeutics300 enrolled19 locationsNCT07456696
Recruiting
Not Applicable

Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal

DepressionPTSD - Post Traumatic Stress DisorderIntimate Partner Violence (IPV)
Possible900 enrolled1 locationNCT06834867
Recruiting
Phase 2

MDMA-Assisted Massed Exposure Therapy for PTSD

Post Traumatic Stress Disorder
Emory University200 enrolled1 locationNCT07288151
Recruiting
Not Applicable

Reported Experience Measurement on Reducing Patient Discomfort in Intensive Care

PTSD - Post Traumatic Stress Disorder
Almaviva Sante1,242 enrolled1 locationNCT07525284
Recruiting
Not Applicable

Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)

Cardiac Arrest (CA)PTSD - Post Traumatic Stress Disorder
Columbia University90 enrolled1 locationNCT07410481
Recruiting
Not Applicable

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

Post Traumatic Stress DisorderTrauma
University of Minnesota30 enrolled1 locationNCT07485231
Recruiting
Not Applicable

Intensive Treatment Versus Standard Weekly Prolonged Exposure for Adults With Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder
Karolinska Institutet140 enrolled1 locationNCT05934175
Recruiting
Not Applicable

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

Chronic PainPost Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center, Houston146 enrolled2 locationsNCT07116109
Recruiting
Not Applicable

TMS-fNIRS Personalized Dosing

Traumatic Brain InjuryPost Traumatic Stress Disorder
Florida State University60 enrolled1 locationNCT05916417
Recruiting
Not Applicable

Stepped Care for Posttraumatic Stress Disorder Study

Post Traumatic Stress Disorder
Boston Medical Center428 enrolled1 locationNCT06947538
Recruiting
Not Applicable

Hyperbaric Oxygen Therapy for Post Traumatic Stress Disorder - a Pragmatic, Double Blinded Randomized Trial

PTSD - Post Traumatic Stress Disorder
Medical Corps, Israel Defense Force72 enrolled1 locationNCT07473362
Recruiting
Not Applicable

Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

Traumatic Brain InjuryPost Traumatic Stress DisorderPTSD
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT07351305
Recruiting
Not Applicable

Digital Biofeedback for Combat Veterans Diagnosed With PTSD

PTSD - Post Traumatic Stress Disorder
NeuroBrave ltd.80 enrolled1 locationNCT07462312
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
University of Texas at Austin600 enrolled2 locationsNCT05467683
Recruiting
Phase 2

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

Traumatic Brain InjuryPost Traumatic Stress Disorder
NYU Langone Health120 enrolled1 locationNCT04550377
Recruiting
Not Applicable

Study of the Effectiveness of VRET Combined With tDCS in the Treatment of PTSD in Ukrainian Veterans and Civilians

PTSD - Post Traumatic Stress Disorder
Malek Bajbouj514 enrolled1 locationNCT06806267