Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

This study tests a skin patch that delivers a calming medication (dexmedetomidine) through the skin to treat agitation in people with Alzheimer's disease who live in care facilities. Agitation — including restlessness, aggression, and distress — is one of the most difficult symptoms of Alzheimer's to manage. **You may be eligible if...** - You (or your loved one) live in a care facility and have been diagnosed with probable Alzheimer's disease - You experience repeated episodes of agitation - A legally authorized representative can provide consent if needed **You may NOT be eligible if...** - You have a history of severe cardiovascular disease or uncontrolled low blood pressure - You are on medications that would interact unsafely with the study drug - You are pregnant - You have severe liver problems affecting drug metabolism Talk to your doctor to see if this trial is right for you.