Agitation Clinical Trials

20 recruiting

Agitation Trials at a Glance

29 actively recruiting trials for agitation are listed on ClinicalTrialsFinder across 6 cities in 37 countries. The largest study group is Phase 2 with 10 trials, with the heaviest enrollment activity in Miami, Anaheim, and Tampa. Lead sponsors running agitation studies include The University of Melbourne, Bristol-Myers Squibb, and Brent Forester.

Browse agitation trials by phase

Treatments under study

About Agitation Clinical Trials

Looking for clinical trials for Agitation? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Agitation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Agitation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Not Applicable

Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)

Alzheimer DementiaAgitation,Psychomotor
Brent Forester50 enrolled5 locationsNCT03926520
Recruiting
Phase 3

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

Alzheimer DiseaseAgitation
Bristol-Myers Squibb600 enrolled241 locationsNCT06937229
Recruiting
Phase 2Phase 3

Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

Agitation Associated With Alzheimer's Disease Dementia
Exciva GmbH300 enrolled14 locationsNCT07284472
Recruiting
Phase 2

Clinical Trial on Agitation in Alzheimer's Dementia

Alzheimer DiseaseAggressionAgitation,Psychomotor+2 more
IGC Pharma, LLC164 enrolled30 locationsNCT05543681
Recruiting
Not Applicable

The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients

Emergence Delirium in Pediatric AnesthesiaPediatric AnesthesiaPostoperative Nausea and Vomiting (PONV)+1 more
Marmara University Pendik Training and Research Hospital150 enrolled2 locationsNCT07534956
Recruiting
Phase 2

Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

Agitation
Teikoku Pharma USA, Inc.150 enrolled3 locationsNCT06052254
Recruiting
Phase 2

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Alzheimer DiseaseAgitation
Celgene120 enrolled52 locationsNCT06808984
Recruiting
Phase 3

Nabilone for Agitation Blinded Intervention Trial

Alzheimer DiseaseAgitation
Sunnybrook Health Sciences Centre112 enrolled6 locationsNCT04516057
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

Agitation Associated With Alzheimer's Dementia
Intra-Cellular Therapies, Inc.320 enrolled69 locationsNCT06651567
Recruiting
Phase 3

Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type

AgitationAlzheimer's Type Dementia
Suven Life Sciences Limited375 enrolled44 locationsNCT05397639
Recruiting
Phase 2

A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia

Agitation Associated With Alzheimer's Disease Dementia
Ono Pharmaceutical Co., Ltd.90 enrolled38 locationsNCT06803823
Recruiting
Not Applicable

The Effect of a Music Intervention on Postictal Agitation in Electroconvulsive Therapy Patients

Music InterventionElectroconvulsive Therapy Treated PatientsAgitation on Recovery From Sedation
Erasmus Medical Center92 enrolled2 locationsNCT06817330
Recruiting

Music Attuned Technology for Care via eHealth (MATCH) in Professional Care

Agitation
The University of Melbourne341 enrolled2 locationsACTRN12625001282471
Recruiting

Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.

Risk BehaviorAgitationHospitalization+1 more
University Hospital, Clermont-Ferrand20 enrolled1 locationNCT05522647
Recruiting
Not Applicable

A Multicomponent Intervention Program to Prevent and Reduce ICU Agitation and Physical Restraint Use

Agitation,Psychomotor
Radboud University Medical Center480 enrolled5 locationsNCT05783505
Recruiting
Phase 2

Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.

Alzheimer DiseaseAgitation in Dementia
Bernard (Barry) Baumel8 enrolled1 locationNCT06781333
Recruiting
Early Phase 1

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

AnxietyAlzheimer DiseaseMild Cognitive Impairment (MCI) Due to Alzheimer's Disease+1 more
Mclean Hospital12 enrolled1 locationNCT04075435
Recruiting
Not Applicable

Virtual Darkness Theraphy for Agitation in Dementia

Agitation in Dementia, Including Alzheimer's Disease
University of Bergen72 enrolled1 locationNCT06451952
Recruiting
Not Applicable

Dexmedetomidine and Agitation After Nasal Surgery

Nasal DiseaseAgitation, Emergence
Fayoum University Hospital50 enrolled1 locationNCT06867302
Recruiting
Phase 2Phase 3

Acute Agitation in Emergency Psychiatry

Agitation
Lone Baandrup132 enrolled1 locationNCT06752616