RecruitingNCT06054854

Biobank for the Identification of Biomarkers in Lung Cancer (BIRD, Biomarkers in Respiratory Disease)

Biobank for the Identification of Diagnostic, Prognostic or Therapeutic (Response and Resistance) Biomarkers in Lung Cancer (Early and Advanced Stages of Lung Cancer Cohort of the BIRD (Biomarkers in Respiratory Disease) Biobank)

Sponsor

University Hospital, Toulouse

Enrollment

3,000 participants

Start Date

Jun 13, 2024

Study Type

OBSERVATIONAL

Conditions

Lung Cancer Lung Nodule

Summary

The BIRD biobank aims at collecting clinical and biological data from patients suffering from a chronic respiratory disease. The lung cancer subpopulation will be divided into two cohorts to identify biomarkers of cancer. One cohort will include patients with supra-centimetric lung nodule(s) whether surveillance, bronchoscopic or radio-guided biopsy or surgery is indicated, patients suspected of lung cancers requiring diagnostic and/or therapeutic bronchial endoscopy and patients with a known early stage lung cancer (early-stage cohort). The second cohort will include known advanced stage lung cancers (III-IV).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a biobank (a collection of biological samples and data) from lung cancer patients and people with suspicious lung nodules. The goal is to find biological markers that can help detect lung cancer earlier and guide treatment decisions. **You may be eligible if...** - You have 1–3 lung nodules on a chest CT scan, including at least one larger than 1 cm - OR you need a bronchoscopy procedure for suspected lung cancer - OR you have been confirmed to have lung cancer (at any stage) before starting any cancer treatment - You are covered by French social security - You can understand the study and sign informed consent **You may NOT be eligible if...** - You are legally deprived of rights or are a protected adult - You cannot understand French - You are already enrolled in another interventional research study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALExtra blood sampling, Non-invasive or leftover samples or medical waste

Extra blood sampling, Urine, Saliva, Stool, Superficial nasal swamp sampling. Bronchoalveolar lavage fluid, Mediastinal node or mass, Peripheral nodule aspiration supernatant, Pleural fluid, Cerebrospinal fluid collection (leftover samples or medical waste). Blood will be collected in larger quantity during a blood test planned as part of the patient's care. Non-invasive or leftover samples or medical waste will be collected on top of the usual diagnosis and during follow-up, depending on the case.