RecruitingPhase 3NCT06058585
The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect
Sponsor
The George Institute
Enrollment
1,000 participants
Start Date
Sep 4, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
CAPTIVATE is an international, multi-centre, Phase III, adaptive, platform, randomised controlled trial in people with chronic kidney disease (CKD). CAPTIVATE aims to find the best treatment, or combination of treatments, that slow the progression of CKD so that fewer people develop kidney failure. CAPTIVATE provides a research platform that allows many treatment-related questions to be answered within a common trial set-up.
Eligibility
Min Age: 18 Years
Inclusion Criteria5
- Age ≥ 18 years
- Known chronic kidney disease from any cause (eGFR ≥25 mL/min/1.73m2)
- Currently receiving standard of care treatment according to treating physician
- Eligible for randomisation in at least one recruiting domain-specific appendix
- Participant and treating physician are willing and able to perform trial procedures
Exclusion Criteria2
- Planned to commence kidney replacement therapy or kidney transplant surgery in next 6 months
- Life expectancy less than 6 months
Interventions
DRUGFinerenone
Finerenone 10mg or 20mg tablets, oral, once daily
DRUGPlacebo Finerenone
Finerenone matched placebo tablets, oral, once daily
Locations(32)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06058585
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