Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine

This trial is testing a pre-transplant chemotherapy preparation regimen (a combination of thiotepa, cyclophosphamide, clarithromycin, and cytarabine) for patients with acute lymphoblastic leukemia (ALL) who have achieved deep remission. **You may be eligible if...** - You have been diagnosed with ALL (a blood cancer) confirmed by bone marrow testing - If you have the Philadelphia chromosome (Ph+ALL): you achieved deep molecular remission early in treatment - If you have Ph-negative B-ALL: your leukemia is undetectable in the bone marrow after chemotherapy - You meet other specific remission criteria based on your ALL subtype **You may NOT be eligible if...** - You have not achieved remission - You have significant organ problems that would make intense chemotherapy unsafe - You have not signed informed consent Talk to your doctor to see if this trial is right for you.