Acute Lymphoblastic Leukemia, Adult Clinical Trials

13 recruiting

Frequently Asked Questions

Common questions about Acute Lymphoblastic Leukemia, Adult clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL

Philadelphia Chromosome Negative ALLAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China77 enrolled1 locationNCT06481241
Recruiting
Not Applicable

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Acute Lymphoblastic Leukemia, AdultPhiladelphia Positive Acute Lymphoblastic Leukemia
Institute of Hematology & Blood Diseases Hospital, China82 enrolled1 locationNCT06481228
Recruiting
Phase 2

CAR T-cell Therapy in Patients With Renal Dysfunction

Multiple MyelomaAcute Lymphoblastic Leukemia, AdultNon-hodgkin Lymphoma,B Cell
Northside Hospital, Inc.20 enrolled1 locationNCT05909059
Recruiting

Incidence of Invasive Fungal Infections Among Patients With Acute Lymphoblastic Leukemia Ph-negative

Invasive Fungal InfectionsAcute Lymphoblastic Leukemia, Adult
Fondazione Policlinico Universitario Agostino Gemelli IRCCS150 enrolled1 locationNCT05750706
Recruiting
Phase 1Phase 2

Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL).

Diffuse Large B Cell LymphomaAcute Lymphoblastic Leukemia, Adult B-CellAcute Lymphoblastic Leukemia, in Relapse+4 more
Essen Biotech75 enrolled1 locationNCT06213636
Recruiting
Phase 2Phase 3

Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL

Acute Lymphoblastic Leukemia, Adult
Shanxi Bethune Hospital50 enrolled1 locationNCT07059156
Recruiting
Phase 1Phase 2

CD19 CAR-T Consolidation Therapy for Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, Adult B-Cell
The First Affiliated Hospital of Soochow University34 enrolled1 locationNCT03984968
Recruiting
Phase 1

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Hematologic MalignancyGvHDGVHD,Acute+8 more
Tr1X, Inc.36 enrolled5 locationsNCT06462365
Recruiting
Phase 1

Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine

Acute Lymphoblastic Leukemia, AdultBurkitt LymphomaLymphoblastic Lymphoma, Adult
Fifth Affiliated Hospital, Sun Yat-Sen University28 enrolled1 locationNCT06060782
Recruiting
Phase 2

A Prospective, Open-label, Randomized Controlled, Multicenter Clinical Study of Haplo-HSCT Using a TBI or TMLI Conditioning Regimen for Adult ALL

Acute Lymphoblastic Leukemia, Adult
The First Affiliated Hospital of Zhengzhou University276 enrolled1 locationNCT06564545
Recruiting
Phase 2

A Prospective, Open-label, Randomized Controlled, Multicenter Clinical Study of MSD-HSCT Using a TBI or TMLI Conditioning Regimen for Adult ALL

Acute Lymphoblastic Leukemia, Adult
The First Affiliated Hospital of Zhengzhou University170 enrolled1 locationNCT06557161
Recruiting
Early Phase 1

Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia

B-Cell Acute Lymphoblastic Leukemia, Adult
The First Affiliated Hospital of Soochow University18 enrolled1 locationNCT06696833
Recruiting
Phase 1Phase 2

Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+3 more
University Hospital Heidelberg68 enrolled2 locationsNCT03676504
Recruiting

Determining the Mechanisms of Loss of CAR T Cell Persistence

Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, PediatricAcute Lymphoblastic Leukemia, Adult+2 more
University College, London50 enrolled3 locationsNCT05809284
Recruiting
Phase 1Phase 2

TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies

Acute Myeloid LeukemiaNon-Hodgkin LymphomaHematologic Malignancy+2 more
Shenzhen TargetRx, Inc.30 enrolled1 locationNCT06206174
Recruiting

Retrospective Observational Study on Infective Complications and Outcome of Patients With ALL Treated With INO

Acute Lymphoblastic LeukemiaInfectionsViral Infection+4 more
Gruppo Italiano Malattie EMatologiche dell'Adulto158 enrolled1 locationNCT06025682
Recruiting

RWE of Pediatric-like Protocol for AYA Patients With Ph-negative ALL

Acute Lymphoblastic Leukemia, Adult
Grupo Argentino de Tratamiento de la Leucemia Aguda100 enrolled2 locationsNCT05127148